Crystal structures of the bacterial protein PglK uncover structural features that suggest how the protein 'flips' lipid-bound oligosaccharide molecules from one side of the cell membrane to the other. See Article p.433
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
References
Perez, C. et al. Nature 524, 433–438 (2015).
Larkin, A. & Imperiali, B. Biochemistry 50, 4411–4426 (2011).
Kern, N. R. et al. Biophys. J. 107, 1885–1895 (2014).
Schenk, B., Fernandez, F. & Waechter, C. J. Glycobiology 11, 61R–70R (2001).
Sanyal, S. & Menon, A. K. ACS Chem. Biol. 4, 895–909 (2009).
Frank, C. G., Sanyal, S., Rush, J. S., Waechter, C. J. & Menon, A. K. Nature 454, E3–E4 (2008).
Alaimo, C. et al. EMBO J. 25, 967–976 (2006).
ter Beek, J., Guskov, A., & Slotboom, D. J. J. Gen. Physiol. 143, 419–435 (2014).
Ward, A., Reyes, C. L., Yu, J., Roth, C. B. & Chang, G. Proc. Natl Acad. Sci. USA 104, 19005–19010 (2007).
Doerrler, W. T., Gibbons, H. S. & Raetz, C. R. J. Biol. Chem. 279, 45102–45109 (2004).
Zhou, G.-P. & Troy, F. A. 2nd. Glycobiology 13, 51–71 (2003).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Verchère, A., Menon, A. Lipid gymnastics. Nature 524, 420–422 (2015). https://doi.org/10.1038/nature15202
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature15202
