Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Biochemistry

Unexpected role for vitamin B2

Nature volume 522, pages 427–428 (2015)Cite this article

Subjects

An enzyme has been found that alters the molecular structure of vitamin B2, adding a fourth ring to its existing three-ring system. The product catalyses new types of chemistry in concert with certain other enzymes. See Letters p.497 & p.502

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Prenylated riboflavin.

Notes

  1. See all news & views

References

  1. White, M. D. et al. Nature 522, 502–506 (2015).

    Article  ADS  CAS  Google Scholar 

  2. Payne, K. A. P. et al. Nature 522, 497–501 (2015).

    Article  ADS  CAS  Google Scholar 

  3. Crane, F. L. Mitochondrion 7, S2–S7 (2007).

    Article  CAS  Google Scholar 

  4. Leppik, R. A., Young, I. G. & Gibson, F. Biochim. Biophys. Acta 436, 800–810 (1976).

    Article  CAS  Google Scholar 

  5. Lin, F., Ferguson, K. L., Boyer, D. R., Lin, X. N. & Marsh, E. N. ACS Chem. Biol. 10, 1137–1144 (2015).

    Article  CAS  Google Scholar 

  6. Weng, J. K. & Chapple, C. New Phytol. 187, 273–285 (2010).

    Article  CAS  Google Scholar 

  7. Krenske, E. H., Patel, A. & Houk, K. N. J. Am. Chem. Soc. 135, 17638–17642 (2013).

    Article  CAS  Google Scholar 

  8. Vinokur, J. M., Korman, T. P., Cao, Z. & Bowie, J. U. Biochemistry 53, 4161–4168 (2015).

    Article  Google Scholar 

  9. Gulmezian, M., Hyman, K. R., Marbois, B. N., Clarke, C. F. & Javor, G. T. Arch. Biochem. Biophys. 467, 144–153 (2007).

    Article  CAS  Google Scholar 

  10. Mukai, N., Masaki, K., Fujii, T., Kawamukai, M. & Iefuji, H. J. Biosci. Bioeng. 109, 564–569 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Catherine F. Clarke and Christopher M. Allan are in the Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA.,

    Catherine F. Clarke & Christopher M. Allan

Authors
  1. Catherine F. Clarke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Christopher M. Allan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Catherine F. Clarke.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Clarke, C., Allan, C. Unexpected role for vitamin B2. Nature 522, 427–428 (2015). https://doi.org/10.1038/nature14536

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature14536

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing