Analyses of ependymoma brain tumours reveal a gene rearrangement in one subtype, but no DNA mutations in two others, suggesting that mechanisms for cancer initiation are broader than is typically thought. See Articles p.445 & p.451
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
A bioelectric model of carcinogenesis, including propagation of cell membrane depolarization and reversal therapies
Scientific Reports Open Access 30 June 2021
-
Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes
Scientific Reports Open Access 18 August 2017
-
Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers
Clinical and Translational Medicine Open Access 06 April 2016
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Tabin, C. J. et al. Nature 300, 143–149 (1982).
Reddy, E. P., Reynolds, R. K., Santos, E. & Barbacid, M. Nature 300, 149–152 (1982).
Parker, M. et al. Nature 506, 451–455 (2014).
Mack, S. C. et al. Nature 506, 445–450 (2014).
Witt, H. et al. Cancer Cell 20, 143–157 (2011).
Vogelstein, B. et al. Science 339, 1546–1558 (2013).
Rausch, T. et al. Cell 148, 59–71 (2012).
Molenaar, J. J. et al. Nature 483, 589–593 (2012).
Lee, R. S. et al. J. Clin. Invest. 122, 2983–2988 (2012).
Plass, C. et al. Nat. Rev. Genet. 14, 765–780 10.1038/nrg3554(2013).
Ben-Porath, I. et al. Nature Genet. 40, 499–507 (2008).
Sausen, M. et al. Nature Genet. 45, 12–17 (2013).
Pugh, T. J. et al. Nature Genet. 45, 279–284 (2013).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Versteeg, R. Tumours outside the mutation box. Nature 506, 438–439 (2014). https://doi.org/10.1038/nature13061
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature13061
This article is cited by
-
Initiation of Cancer: The Journey From Mutations in Somatic Cells to Epigenetic Changes in Tissue-resident VSELs
Stem Cell Reviews and Reports (2024)
-
Why Do We Care More About Disease than Health?
Phenomics (2022)
-
A bioelectric model of carcinogenesis, including propagation of cell membrane depolarization and reversal therapies
Scientific Reports (2021)
-
Revisiting D.W. Smithers’s “Cancer: An Attack on Cytologism” (1962)
Biological Theory (2020)
-
Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes
Scientific Reports (2017)