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Structural biology

Meet the B family

Nature volume 499, pages 417–418 (2013)Cite this article

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The first crystal structures of class B G-protein-coupled receptors have been solved. They reveal features that might inform drug-development strategies for diseases ranging from osteoporosis to diabetes. See Articles p.438 & p.444

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Figure 1: Structural features of class B GPCRs.

Notes

  1. *This article and the papers under discussion3,4 were published online on 17 July.

References

  1. Fredriksson, R., Lagerström, M. C., Lundin, L. G. & Schiöth, H. B. Mol. Pharmacol. 63, 1256–1272 (2003).

    Article  CAS  Google Scholar 

  2. Overington, J. P., Al-Lazikani, B. & Hopkins, A. L. Nature Rev. Drug Discov. 5, 993–996 (2006).

    Article  CAS  Google Scholar 

  3. Hollenstein, K. et al. Nature 499, 438–443 (2013).

    Article  ADS  CAS  Google Scholar 

  4. Siu, F. Y. et al. Nature 499, 444–449 (2013).

    Article  ADS  CAS  Google Scholar 

  5. Dong, M. et al. FASEB J. 26, 5092–5105 (2012).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Patrick M. Sexton and Denise Wootten are at the Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.,

    Patrick M. Sexton & Denise Wootten

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  1. Patrick M. Sexton
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  2. Denise Wootten
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Correspondence to Patrick M. Sexton or Denise Wootten.

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Sexton, P., Wootten, D. Meet the B family. Nature 499, 417–418 (2013). https://doi.org/10.1038/nature12413

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