Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell biology

Death brings new life to muscle

Fusion of muscle cells called myoblasts underlies the generation and maintenance of skeletal muscle throughout an animal's life. Emerging data indicate that cell death acts as a signal to enhance these processes in mammals. See Letter p.263

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Helping hand from a dying cell.

Notes

  1. *This article and the paper under discussion were published online on 24 April 2013.

References

  1. Rochlin, K., Yu, S., Roy, S. & Baylies, M. K. Dev. Biol. 341, 66–83 (2010).

    Article  CAS  Google Scholar 

  2. Abmayr, S. M. & Pavlath, G. K. Development 139, 641–656 (2012).

    Article  CAS  Google Scholar 

  3. Gumienny, T. L. et al. Cell 107, 27–41 (2001).

    Article  CAS  Google Scholar 

  4. Hochreiter-Hufford, A. E. et al. Nature 497, 263–267 (2013).

    Article  ADS  CAS  Google Scholar 

  5. Park, D. et al. Nature 450, 430–434 (2007).

    Article  ADS  CAS  Google Scholar 

  6. Sessions, A. & Horwitz, A. F. FEBS Lett. 134, 75–78 (1981).

    Article  CAS  Google Scholar 

  7. van den Eijnde, S. M. et al. J. Cell Sci. 114, 3631–3642 (2001).

    CAS  PubMed  Google Scholar 

  8. Jeong, J. & Conboy, I. M. Biochem. Biophys. Res. Commun. 414, 9–13 (2011).

    Article  CAS  Google Scholar 

  9. Chargé, S. B. P. & Rudnicki, M. A. Physiol. Rev. 84, 209–238 (2004).

    Article  Google Scholar 

  10. Fernando, P., Kelly, J. F., Balazsi, K., Slack, R. S. & Megeney, L. A. Proc. Natl Acad. Sci. USA 99, 11025–11030 (2002).

    Article  ADS  CAS  Google Scholar 

  11. Leikina, E. et al. J. Cell Biol. 200, 109–123 (2013).

    Article  CAS  Google Scholar 

  12. Gauster, M., Moser, G., Orendi, M. & Huppertz, B. Placenta 30, S49–S54 (2009).

    Article  Google Scholar 

  13. Bergmann, A. & Steller, H. Sci. Signal. 3, re8 (2010).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mary K. Baylies.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yu, S., Baylies, M. Death brings new life to muscle. Nature 497, 196–197 (2013). https://doi.org/10.1038/nature12097

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12097

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing