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In this Letter, the maternal species listed for hybrid BE-1 is attributed to Macropus eugenii. However, our ongoing studies show that the maternal complement of chromosomes in BE-1 was inherited from a Macropus rufogriseus female. The centromeres of M. rufogriseus chromosomes are extended in comparison to all other macropod species. The extent, therefore, to which the centromere extensions shown in Fig. 4 can be attributed to hybrid-specific amplification of the retrolement KERV-1 cannot be precisely determined. Nevertheless, Southern analysis confirms that this retroelement is present at a 20% higher copy number in the hybrid's genome compared with that of its parents, and FISH analysis shows KERV-1 localization only to centromeres in the hybrid. Our conclusions regarding hybrid-specific undermethylation in this hybrid individual are not affected because M. rufogriseus shows methylation levels typical of species within the macropod group. Hybrid-specific undermethylation and genome rearrangement also remain true for the Petrogale hybrids we presented.
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The online version of the original article can be found at 10.1038/29985
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Waugh O'Neill, R., O'Neill, M. & Marshall Graves, J. Correction: Corrigendum: Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid. Nature 420, 106 (2002). https://doi.org/10.1038/nature01162
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DOI: https://doi.org/10.1038/nature01162
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