Long Course Article

Recently characterized soft tissue tumors that bring biologic insight

  • Modern Pathology volume 27, pages S98S112 (2014)
  • doi:10.1038/modpathol.2013.172
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Previously unrecognized but clinicopathologically (and often molecularly) distinct types of soft tissue tumor continue to be characterized, allowing wider recognition, more consistent application of diagnostic criteria, more reliable prediction of tumor behavior and enhancement of existing classification schemes. Examples of such ‘entities’ that have become much better understood over the past decade or so include deep ‘benign’ fibrous histiocytoma, hemosiderotic fibrolipomatous tumor, PEComa, spindle cell liposarcoma, myoepithelial tumors of soft tissue and spindle cell/sclerosing rhabdomyosarcoma. These tumor types, as well as the insights which they have engendered, are briefly reviewed here.

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Author information


  1. Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    • Christopher D M Fletcher


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Competing interests

The author declares no conflict of interest.

Corresponding author

Correspondence to Christopher D M Fletcher.