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Mutations and karyotype in myelodysplastic syndromes: TP53 clusters with monosomal karyotype, RUNX1 with trisomy 21, and SF3B1 with inv(3)(q21q26.2) and del(11q)
Blood Cancer Journal Open Access 18 December 2017
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Acknowledgements
This work was supported by grants from the Priority Academic Program Development of Jiangsu Higher Education Institutions, the Natural Science Foundation of China (81570139, 81370626, 81070416, 81300424, 81400112), the national key research and development program, 2016YFC0902800), the Innovation Capability Development Project of Jiangsu Province (BM2015004), and Jiangsu Province Natural Science Fund (BE2015639).
Author contributions
SC and AS were the principal investigators. TZ, YX, JP, QW, LW and DP performed most of the experiments. HL performed structural model of RUNX1. SC and AS wrote the manuscript.
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Zhang, T., Xu, Y., Pan, J. et al. High frequency of RUNX1 mutation in myelodysplastic syndrome patients with whole-arm translocation of der(1;7)(q10;p10). Leukemia 31, 2257–2260 (2017). https://doi.org/10.1038/leu.2017.228
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DOI: https://doi.org/10.1038/leu.2017.228
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