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Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL Network Phase II Trial

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Acknowledgements

We thank the patients, nurses, physicians and data managers (Antonella Fiorillo). A special thanks to Marco Ladetto, MD, for the scientific and material support and to Sara Fortin for graphical assistance. This work was supported by the EU (LSHC-CT 2004-503351), the Lymphoma Research Foundation (New York) and Bayer-Schering. SF was supported by Progetto di Rilevante Interesse Nazionale (PRIN 2009) from Ministero Italiano dell' Università e della Ricerca (MIUR), Roma, Italy (code: 7.07.02.60 AE01); Progetto di Ricerca Sanitaria Finalizzata 2009, head unit: Divisione di Ematologia S Cortellazzo, AOS Maurizio, Bolzano/Bozen, Italy (code: RF-2009-1469205); Progetto di Ricerca Sanitaria Finalizzata 2010 (head unit: Divisione di Ematologia, AOS Maurizio, Bolzano/Bozen, Italy; code: RF-2010-2307262), Fondi di Ricerca Locale, Università degli Studi di Torino, Torino, Italy; Fondazione Neoplasie del Sangue (FO. NE. SA), Torino, Italy.

Author contributions

MD, MU and WH designed the study. SF, MD and PG wrote the report. MU and MD supervised the clinical conduction of the study and data analysis. SF, APa, OW and MU supervised data collection and analyzed data. OW and MU reviewed and assisted in writing the manuscript. RP did the statistical analysis. APa, RF, CWS, APe, LB, LT, JF, UK and OW recruited the patients.

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Correspondence to S Ferrero.

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Competing interests

Off-label use: Zevalin for the treatment of relapsed MCL. SF: Celgene-Mundipharma, Speakers Honoraria. LT: Spectrum Pharmaceuticals, research funding; CWS: Bayer, Speakers Bureau; Spectrum, Membership on an entity‘s Board of Directors or advisory committees, Speakers Honoraria. Gilead, Janssen-Cilag, Roche, Pfizer and Mundipharma, Advisory Board; Roche, Mundipharma, Pfizer and Gilead, Speakers Honoraria; UK: Spectrum Pharmaceuticals, Advisory board, Consultancy; Roche, Advisory board, Consultancy. MD: Jannsen-Celgene-Pfizer, Membership on an entity‘s Board of Directors or advisory committees, Speakers Bureau, support of ITS; Roche, Speakers Bureau, support of ITS; Mundipharma, support of ITS. The other authors declare no conflict of interest.

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This manuscript is an original paper and has not been submitted or published elsewhere. Data from interim analyses were presented in part at the 2013 American Society of Hematology (ASH) meeting.

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Ferrero, S., Pastore, A., Scholz, C. et al. Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL Network Phase II Trial. Leukemia 30, 984–987 (2016). https://doi.org/10.1038/leu.2015.215

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