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Abdominal distention in an inbred mouse

Lab Animal volume 42, pages 209–211 (2013)Cite this article

The National Laboratory Animal Center (NLAC) of Taiwan is a rodent breeding facility that produces specific pathogen–free (SPF) laboratory rodents. NLAC is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International and serves as a multi-functional laboratory animal resource center, providing quality laboratory animals to the scientific and industrial community.

We carry out routine health monitoring and pathology, including diagnostic histopathological examinations and phenotyping, of all rodents. NLAC animal technicians are trained to conduct daily observations and to evaluate and recognize humane endpoints1. In cases where pregnancy, organomegaly or tumor growth (intra-abdominal growth) is detected, body condition scoring is used instead of body weight assessment in rodents to minimize pain and distress2.

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Figure 1
Figure 2: The mouse was euthanized and a necropsy was carried out.
Figure 3: The cyst was examined microscopically.

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Acknowledgements

We thank Wei-Jen Lai (NLAC) and Nouchee Yang (Experimental Pathology Laboratories, Inc.) for their contributions to this report.

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Authors and Affiliations

  1. National Laboratory Animal Center, National Applied Research Laboratories, Taipei, Taiwan

    Tzu-Yu Chen,  Kan-Hung Lee &  Yu-Ling Chen

  2. Experimental Pathology Laboratories, Inc., Research Triangle Park, NC

    John Curtis Seely

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  1. Tzu-Yu Chen
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  2. Kan-Hung Lee
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  3. Yu-Ling Chen
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Correspondence to Tzu-Yu Chen.

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Chen, TY., Lee, KH., Chen, YL. et al. Abdominal distention in an inbred mouse. Lab Anim 42, 209–211 (2013). https://doi.org/10.1038/laban.167

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