Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Article
  • Published:

Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management

Abstract

Objective:

To define the impact of care standardization on caffeine and cardiorespiratory monitoring at neonatal intensive care unit (NICU) discharge.

Study Design:

Electronic records were abstracted for infants aged 24–36 weeks gestation with birth weights appropriate for gestational age. Infants who died, transferred prior to discharge, had major pulmonary anomalies, required a home monitor for mechanical ventilation or had a family history of sudden infant death syndrome were excluded. Data and records were used to indicate when the new definition of clinically significant cardiopulmonary events (CSCPEs) and concurrent education was implemented. Preimplementation and postimplementation cohorts were compared.

Results:

Incidence fell from 74% diagnosed with apnea of prematurity at baseline to 49% diagnosed with CSCPE postimplementation (P<0.001). Infants discharged on caffeine reduced from 17% to 5% (P<0.001), and home monitor use also fell from 54% to 16% (P<0.001).

Conclusion:

Standardizing definitions and treatments reduced the use of caffeine and cardiorespiratory monitors upon NICU dismissal.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

References

  1. National Institutes of Health Consensus Development Conference on Infantile Apnea and Home Monitoring, Sept 29 to Oct 1, 1986. Pediatrics 1987; 79 (2): 292–299.

  2. Stokowski LA . A primer on apnea of prematurity. Adv Neonatal Care 2005; 5 (3): 155–170; quiz 171–174.

    Article  PubMed  Google Scholar 

  3. Daily WJ, Klaus M, Meyer HB . Apnea in premature infants: monitoring, incidence, heart rate changes, and an effect of environmental temperature. Pediatrics 1969; 43 (4): 510–518.

    CAS  PubMed  Google Scholar 

  4. Janvier A, Khairy M, Kokkotis A, Cormier C, Messmer D, Barrington KJ . Apnea is associated with neurodevelopmental impairment in very low birth weight infants. J Perinatol 2004; 24 (12): 763–768.

    Article  PubMed  Google Scholar 

  5. Barrington K, Finer N . The natural history of the appearance of apnea of prematurity. Pediatr Res 1991; 29 (4 Pt 1): 372–375.

    Article  CAS  PubMed  Google Scholar 

  6. Finer NN, Higgins R, Kattwinkel J, Martin RJ . Summary proceedings from the apnea-of-prematurity group. Pediatrics 2006; 117 (3 Pt 2): S47–S51.

    Article  PubMed  Google Scholar 

  7. Miller HC, Behrle FC, Smull NW . Severe apnea and irregular respiratory rhythms among premature infants; a clinical and laboratory study. Pediatrics 1959; 23 (4): 676–685.

    CAS  PubMed  Google Scholar 

  8. Miller MJ, Martin RJ . Apnea of prematurity. Clin Perinatol 1992; 19 (4): 789–808.

    CAS  PubMed  Google Scholar 

  9. Butler TJ, Firestone KS, Grow JL, Kantak AD . Standardizing documentation and the clinical approach to apnea of prematurity reduces length of stay, improves staff satisfaction, and decreases hospital cost. Jt Comm J Qual Patient Saf 2014; 40 (6): 263–269.

    Article  PubMed  Google Scholar 

  10. Hasibeder WR . Does standardization of critical care work? Curr Opin Crit Care 2010; 16 (5): 493–498.

    Article  PubMed  Google Scholar 

  11. Vermont Oxford Network. Past NICQ Collaboratives (cited 18 May 2015). Available from https://public.vtoxford.org/quality-education/quality-improvement-collaboratives/nicq-past-collaboratives.

Download references

Acknowledgements

We thank Jared Shaw, clinical systems analyst, for his assistance in accessing the data used in this manuscript. We also thank the team who led the implementation of these changes and the staff of the Neonatal Special Nurseries who initiated these changes and adapted their practices to the benefit of our patients. This work was funded by a grant from the Wichita Medical Research and Education Foundation.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to B T Bloom.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Powell, M., Ahlers-Schmidt, C., Engel, M. et al. Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management. J Perinatol 37, 88–90 (2017). https://doi.org/10.1038/jp.2016.167

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jp.2016.167

This article is cited by

Search

Quick links