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  • Original Article
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Failure of early nasal continuous positive airway pressure in preterm infants of 26 to 30 weeks gestation

Abstract

Objective:

To identify variables associated with early nasal continuous positive airway pressure (ENCPAP) failure in preterm neonates less than 30 weeks gestational age.

Study Design:

Multicenter prospective study including 131 preterm newborns, over a period of 2 years. Patients and respiratory variables were assessed using univariate analysis.

Result:

Variables associated with ENCPAP failure were: the need of resuscitation with a FiO2>0.30; a CPAP pressure of 6.4±1.2 cm H2O; the need of a FiO2 of 0.40 in the first 4 h of life; male gender maintaining the need of a FiO2>0.25 in the first 4 h of life; and respiratory distress syndrome with criteria for surfactant administration.

Conclusion:

The need for oxygen in resuscitation and maintained in first hours of life, male gender, a CPAP pressure over 5 cm H2O and surfactant need are predictors of ENCPAP failure in preterm neonates 26 to 30 weeks gestational age.

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Correspondence to G Rocha.

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Rocha, G., Flôr-de-Lima, F., Proença, E. et al. Failure of early nasal continuous positive airway pressure in preterm infants of 26 to 30 weeks gestation. J Perinatol 33, 297–301 (2013). https://doi.org/10.1038/jp.2012.110

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  • DOI: https://doi.org/10.1038/jp.2012.110

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