Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Article
  • Published:

Covered skin transcutaneous bilirubin estimation is comparable with serum bilirubin during and after phototherapy

Abstract

Objective:

To determine whether transcutaneous bilirubin (TcB) from covered skin (TcB-C) during and after discontinuing phototherapy (PHT) is reliable in treating neonatal jaundice.

Study Design:

In this prospective observational study, before starting PHT, part of the forehead was covered. TcB-C and TcB from exposed skin (TcB-E) to PHT were measured before starting PHT, on a 12-hourly basis while receiving PHT and 6 h after stopping PHT. We used ANOVA (analysis of variance) and Bonferroni's t-tests.

Result:

A total of 39 infants were enrolled (mean gestation 39 weeks, 51% males and 80% Hispanic). The mean TSB over all time periods was 10.9±2.4, TcB-C 10.9±2.4 and TcB-E 7.2±3.4. Before PHT, there were no significant differences in bilirubin by all three techniques. TcB-C was not significantly different from TSB at any time point. However, TcB-E was significantly lower during PHT and after stopping PHT.

Conclusion:

TcB-C is a reliable method in the management of neonatal jaundice.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bhutani VK, Gourley GR, Adler S, Kreamer B, Dalin C, Johnson LH . Noninvasive measurement of total serum bilirubin in multiracial predischarge newborn population to assess the risk of severe hyperbilirubinemia. Pediatrics 2000; 106 (2): E17. Available at: www.pediatrics.org/cgi/content/full/106/2/e17.

    Article  CAS  Google Scholar 

  2. Maisels MJ, Newman TB . Jaundice in full-term and near- term babies who leave the hospital within 36 h. Clin Perinatol 1998; 25: 295–302.

    Article  CAS  Google Scholar 

  3. Moyer VA, Ahn C, Sneed S . Accuracy of clinical judgment in neonatal jaundice. Arch Pediatr Adolesc Med 2000; 154: 391–394.

    Article  CAS  Google Scholar 

  4. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia Management. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004; 114: 297–316.

    Article  Google Scholar 

  5. Rubaltelli FF, Gourley GR, Loskamp N, Modi N, Roth-Kleiner M, Sender A et al. Transcutaneous bilirubin measurement: a multicenter evaluation of a new device. Pediatrics 2001; 107: 1264–1271.

    Article  CAS  Google Scholar 

  6. Maisels MJ, Kring E . Transcutaneous bilirubinometery decreases the need for serum bilirubin measurement and saves money. Pediatrics 1997; 199: 599–601.

    Article  Google Scholar 

  7. Ozkan H, Oren H, Dumen N, Duman M . Dermal bilirubin kinetics during phototherapy in term neonates. Acta Pediatr 2003; 92: 577–581.

    Article  CAS  Google Scholar 

  8. Varvarigou A, Fouzas S, Skylogianni E, Mantagou L, Bougioukou D, Mantagos S . Transcutaneous bilirubin normogram for prediction of significant neonatal hyperbilirubinemia. Pediatrics 2009; 124 (4): 1052–1059.

    Article  Google Scholar 

  9. Engle WD, Jackson GL, Sendelbach D, Manning D, Frawley WH . Assessment of a transcutaneous device in the evaluation of neonatal hyperbilirubinemia in a primarily Hispanic population. Pediatrics 2002; 110 (1 part 1): 61–67.

    Article  Google Scholar 

  10. Tan KL, Dong F . Transcutaneous bilirubinmetery during and after phototherapy. Acta Paediatr 2003; 92: 327–331.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This study could have not been possible without the help of Brandi Listi NP, Wendie Saenz NP, Audrey Sanders NP and the nurses in the newborn nursery.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S K Jain.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fonseca, R., Kyralessa, R., Malloy, M. et al. Covered skin transcutaneous bilirubin estimation is comparable with serum bilirubin during and after phototherapy. J Perinatol 32, 129–131 (2012). https://doi.org/10.1038/jp.2011.66

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jp.2011.66

Keywords

This article is cited by

Search

Quick links