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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Hyperleukocytosis in a premature infant with intrauterine herpes simplex encephalitis

Journal of Perinatology volume 32, pages 469–472 (2012)Cite this article

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Abstract

Herpes encephalitis is a rare but devastating infection in premature infants. We report a 29 week gestation infant with severe intrauterine cutaneous and central nervous system herpes accompanied by hyperleukocytosis. Leukemoid reactions are not uncommon in this population, but the association of herpes encephalitis and a leukemoid reaction or hyperleukocytosis has not been reported previously.

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Acknowledgements

We thank John W Bishop MD, Director of Anatomic Pathology, UC Davis Medical Center, for review of the placental pathology and special staining. This work was financially supported by MU: NIH HD059127 (NICHD). This publication was also made possible by Grant number UL1 RR024146 from the National Center for Research Resources (NCRR), a component of the NIH.

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  1. Department of Pediatrics, University of California, Davis School of Medicine, Sacramento, CA, USA

    M A Underwood, A E Wartell & R A Borghese

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  1. M A Underwood
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  2. A E Wartell
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  3. R A Borghese
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Correspondence to M A Underwood.

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Underwood, M., Wartell, A. & Borghese, R. Hyperleukocytosis in a premature infant with intrauterine herpes simplex encephalitis. J Perinatol 32, 469–472 (2012). https://doi.org/10.1038/jp.2011.138

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