Abstract
We report here 20 single-nucleotide polymorphisms (SNPs), including 15 novel ones, in six genes that are considered to be candidates for long QT syndrome (LQTS): 2 SNPs in KCNB1, 3 in KCND3, 3 in KCNJ11, 7 in ABCC9, 3 in ADRB1, and 2 in SLC18A2. We also examined their allelic frequencies in a Japanese sample population of LQTS-affected and nonaffected individuals. These data will be useful for genetic association studies designed to investigate acquired arrhythmias.
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Received: December 12, 2000 / Accepted: December 23, 2000
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Iwasa, H., Kurabayashi, M., Nagai, R. et al. Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome. J Hum Genet 46, 158–162 (2001). https://doi.org/10.1007/s100380170106
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DOI: https://doi.org/10.1007/s100380170106
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