Abstract
Matrix Gla protein (MGP) is an 84-residue, vitamin K-dependent protein expressed by chondrocytes and vascular smooth muscle cells, and is a potent regulator of calcium deposition in cartilage and arterial wall. We isolated a polymorphic dinucleotide CA repeat marker from a genomic clone containing the human MGP gene. This polymorphism will be useful in genetic studies of arteriosclerosis and osteoporosis.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Additional information
Received: November 5, 1997 / Accepted November 27, 1997
Rights and permissions
About this article
Cite this article
Watanabe, I., Tsukamoto, K., Shiba, T. et al. Isolation and radiation hybrid mapping of dinucleotide repeat polymorphism at the human matrix Gla protein (MGP) locus. J Hum Genet 43, 75–76 (1998). https://doi.org/10.1007/s100380050044
Published:
Issue Date:
DOI: https://doi.org/10.1007/s100380050044