Summary
Polymorphism of the B subunit of human coagulation factor XIII was investigated in a total of 119 plasma samples from unrelated adult Japanese using agarose gel electrophoresis followed by immunofixation. Three common phenotypes were observed, which corresponded to the types 1, 1–3 and 3 reported by Board (1980) in Australians. The estimated allele frequencies ofF13B *1 andF13B *3 were 0.303 and 0.697, respectively. The observed numbers of the phenotypes were in good agreement with those expected on the basis of Hardy-Weinberg's law. These results are not inconsistent with the hypothesis that these phenotypes are controlled by a pair of autosomal, codominant alleles.
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Nishigaki, T., Omoto, K. Genetic polymorphism of the B subunit of human coagulation factor XIII in Japanese. Jap J Human Genet 27, 265–270 (1982). https://doi.org/10.1007/BF01901322
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DOI: https://doi.org/10.1007/BF01901322