Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Lead powder use for skin care and elevated blood lead level among children in a Chinese rural area

Abstract

To investigate the association between lead powder use, as folk skin care, and blood lead level (BLL) in children, we studied 222 children up to 14-years old living in a Chinese rural area and administered a face to face interview with their parents to collect information on lead powder use and other potential exposure. We measured children's BLL at baseline and 2 years later after an intervention. The children were divided into three categories according to their use of lead powder: regular use, irregular use and never use. We applied multivariate linear regression to determine the association between lead powder use and elevated BLL. The average BLL of all children was 18 μg/dl; 56% of them had BLL of 10 μg/dl or higher. Lead powder use was significantly associated with elevated BLL. After adjusting for potential confounders the BLL of regular and irregular users was higher than non-users by 3.11 μg/dl and 1.47 μg/dl, respectively. Duration of lead powder use was positively associated with BLL, but the time since last use was inversely associated. A significant BLL reduction was observed 2 years later, and the greatest reduction (21 μg/dl) was seen in the youngest group of regular users. This study showed that traditional use of lead powder for a skin care purpose was a major contributor to elevated BLL in these children.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

Abbreviations

BLL:

Blood Lead Level

CDC:

Center for Disease Control and Prevention

CTM:

Chinese Traditional Medicine

IQ:

Intelligence Quotient

US:

United States

WHO:

World Health Organization

References

  • Auyeung T.W., Chang K.K., To C.H., Mak A., and Szeto M.L. Three patients with lead poisoning following use of a Chinese herbal pill. Hong Kong Med J 2002: 8: 60–62.

    CAS  PubMed  Google Scholar 

  • Bian G.G. Lead level in blood for Chinese countryside children (in Chinese). Huangjing Kexue yu Jishu 2008: 31: 101–106.

    CAS  Google Scholar 

  • Chen A., Dietrich K.N., Ware J.H., Radcliffe J., and Rogan W.J. IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environ Health Perspect 2005: 113 (5): 597–601.

    Article  CAS  Google Scholar 

  • Dong G.Q., Yi W.F., and Lu X.Y. Clinical Characteristics of 16 Cases of High Blood Lead or Lead Poisoning Caused by Using lead Powder in Infants (in Chinese). Shi Yong Er Ke Lin Chuang Za Zhi 2009: 24 (18): 1427–1428.

    Google Scholar 

  • Duzgoren-Aydin N.S. Sources and characteristics of lead pollution in the urban environment of Guangzhou. Sci Total Environ 2007: 385: 182–195.

    Article  CAS  Google Scholar 

  • Fan Y.F., Li Z.H., and Sun S.C. Lead powder cause lead poisoning: one case report (in Chinese). Zhongguo Er Tong Bao Jian Za Zhi 2002: 10 (4): 288.

    Google Scholar 

  • Filon F.L., Boeniger M., Maina G., Adami G., Spinelli P., and Damian A. Skin absorption of inorganic lead (Pb O) and the effect of skin cleansers. J Occup Environ Med 2006: 48: 692–699.

    Article  CAS  Google Scholar 

  • Grant L.D. Getting the lead out: important expsosure science contributions. J Expo Sci Environ Epidemiol 2010: 20: 577–578.

    Article  Google Scholar 

  • Gulson B.L., Davis J.J., and Smith J.B. Paint as a source of recontamination of houses in urban environments and its role in maintaining elevated blood leads in children. Sci Total environ1 1995: 64 (3): 221–235.

    Article  Google Scholar 

  • He K.M., Wang S.Q., and Zhang J.L. Blood lead levels of children and its trend in China. Sci Total Environ 2009: 407: 3986–3993.

    Article  CAS  Google Scholar 

  • Huo X., Peng L., Xu X.J., Zheng L.K., Qiu B., and Qi Z.L., et al. Elevated Blood Lead Levels of Children in Guiyu, an Electronic Waste Recycling Town in China. Environ Health Perspect 2007: 115: 1113–1117.

    Article  CAS  Google Scholar 

  • Jacobs D.E., Clickner R.P., Zhou J.Y., Viet S.M., Marker D.A., and Rogers J.W., et al. The Prevalence of lead-based paint hazards in US housing. Environ Health Perspect 2002: 110: A599–A606.

    Article  CAS  Google Scholar 

  • Ji A.L., Wang F., Luo W.J., Yang R.H., Chen J.Y., and Cai T.J. Lead poisoning in China: a nightmare from industrialization. The Lancet 2011: 377: 1474–1476.

    Article  Google Scholar 

  • Jones T.F., Moore W.L., Craig A.S., Reasons R.L., Craig A.S., and Reasons R.L., et al. Hidden threats: lead poisoning from unusual sources. Pediatrics 1999: 104: 1223–1225.

    CAS  PubMed  Google Scholar 

  • Jordan C., Yust B.L., Robison L.L., Hannan P., and Deinard A.S. A randomized trial of education to prevent lead burden in children at high risk for lead exposure: efficacy as measured by blood lead monitoring. Environ Health Perspect 2003: 111: 1947–1951.

    Article  CAS  Google Scholar 

  • Lanphear B.P., and Roghmann K.J. Pathways of Lead Exposure in Urban Children. Environ Res 1997: 74: 67–73.

    Article  CAS  Google Scholar 

  • Levin R., Brown M.J., Kashtock M.E., Jacobs D.E., Whelan E.A., Rodman J., Schock M.R., Padilla A., and Sinks T. Lead Exposures in US Children, 2008: implications for Prevention. Environ Health Perspect 2008: 116: 1285–1293.

    Article  CAS  Google Scholar 

  • Lin G.Z., Yan C.H., and Li K. Investigation on Lead Poisoning with Red Lead Toilet Powder in Children (in Chinese). Shi Yong Er Ke Lin Chuang Za Zhi 2010: 25 (6): 128–129.

    Google Scholar 

  • Lin S.H., Wang X.R., Yu S.-K., Tang W.J., Miao J.Y., and Wu S.Y., et al. Environmental Lead Pollution and Elevated Blood Lead Level among Children Living in a Rural Area of China. Am J Public Health 2011: 101 (5): 834–841.

    Article  Google Scholar 

  • Mcelvaine M.D., Harder E.M., Johnson L., Baer R.D., and Satzger R.D. Lead poisoning from the use of Indian folk medicines. JAMA 1990: 264 (17): 2212–2213.

    CAS  PubMed  Google Scholar 

  • Meyer P.A., Brown M.J., and Falk H. Global approach to reducing lead exposure and poisoning. Mutat Res 2008: 659: 166–175.

    Article  CAS  Google Scholar 

  • Miller D.T., Paschal D.C., Gunter E.W., Stroud P.E., and D’Angelo J. Determination of lead in blood using electrothermal atomisation atomic absorption spectrometry with a l’vov platform and matrix modifier. Analyst 1987: 112: 1701–1704.

    Article  CAS  Google Scholar 

  • Peng Y.J., Yu Y.H., and Gu X.X. Report on 55 cases of lead poisoning caused by plumbic folk prescription (in Chinese). Zhongguo Gongye Yixue Za zhi 2008: 21 (2): 75.

    Google Scholar 

  • Rhor M. Lead Poisoning Caused by Many Traditional Cures (http://www.nysun.com/national/lead-poisoning-caused-by-many-traditional-cures/69985/) accessed on 4 November, 2010.

  • Shen X., Rosen J.F., Guo D., and Wu S. Childhood lead poisoning in China. Sci Total Environ 1996: 181 (2): 101–109.

    Article  CAS  Google Scholar 

  • Sun C.C., Wong T.T., Hwang Y.H., Chao K.Y., Jee S.H., and Wang J.D. Percutaneous absorption of inorganic lead compounds. AIHA J (Fairfax, Va) 2002: 63 (5): 641–646.

    Article  CAS  Google Scholar 

  • US CDC. Lead Poisoning Associated with Use of Litargirio --- Rhode Island, 2003. MMWR 2005: 54 (09): 227–229.

    Google Scholar 

  • Wang S.Q., and Zhang J.L. Blood lead levels in children, China. Environ Rres 2006: 101 (3): 412–418.

    Article  CAS  Google Scholar 

  • Woolf A.D., and Woolf N.T. Childhood lead poisoning in 2 families: associated with spices used in food preparation. Pediatrics 2005: 116 (2): 314–318.

    Article  Google Scholar 

  • Wu Y., Huang Q., and Zhou X., et al. Study on the effects of lead from small industry of battery recycling on environment and children's health (in Chinese). Zhonghua Liu Xing Bing Xue Za Zhi 2002: 23 (3): 167–171.

    PubMed  Google Scholar 

  • Yan C.H., and Shen X.M. Study review and prospect for saturnism prevention and control among Chinese children (in Chinese). Zhonghua Yu Fang Yi Xue Za Zhi 2008: 42 (3): 147–150.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xiao-Rong Wang.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lin, SH., Wang, XR., Yu, I. et al. Lead powder use for skin care and elevated blood lead level among children in a Chinese rural area. J Expo Sci Environ Epidemiol 22, 198–203 (2012). https://doi.org/10.1038/jes.2011.46

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jes.2011.46

Keywords

This article is cited by

Search

Quick links