Abstract
New nine insecticidal antibiotics designated yaequinolones were isolated from the culture broth of the fungal strain Penicillium sp. FKI-2140 by solvent extraction, centrifugal partition chromatography and HPLC. Yaequinolones showed growth inhibitory activity against brine shrimp (Artemia salina). Among them, yaequinolone F has the most potent activity with MIC value of 0.19 μg/ml.
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Uchida, R., Imasato, R., Yamaguchi, Y. et al. Yaequinolones, New Insecticidal Antibiotics Produced by Penicillium sp. FKI-2140. J Antibiot 59, 646–651 (2006). https://doi.org/10.1038/ja.2006.86
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DOI: https://doi.org/10.1038/ja.2006.86
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