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Reduced neural response to food cues following exercise is accompanied by decreased energy intake in obese adolescents

International Journal of Obesity volume 40, pages 77–83 (2016)Cite this article

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Abstract

Background:

Acute exercise has been found to favor a transient anorexigenic effect in obese adolescents. Although the role of some gastro-peptides has been suggested as an explanation for this observed reduced energy intake after exercise, it is unknown whether neural pathways involved in the regulation of food intake are modulated in youth.

Methods:

Body composition (dual-energy X-ray absorptiometry) and aerobic capacities were assessed in 19 obese adolescent boys. Participants were randomized to remain at rest in a sitting position (CON condition) or to exercise 45 min at 65% of their maximal capacities (EX condition) by the end of the morning. An attentional computer task with electroencephalography recording was completed immediately after the exercise or sitting period to measure an event-related component (P3b) reflecting the level of cognitive engagement in the processing of food cues. A lunch test-meal was offered ad libitum and appetite feelings assessed at regular intervals using visual analog scales.

Results:

The 45-min cycling exercise set at 65% VO2max induced a mean energy expenditure of 399±75 kcal. Both absolute (P<0.05) and relative (P<0.001) subsequent energy intake were significantly reduced after EX (1037±260 and 639±256 kcal, respectively) compared with CON (1116±243 and 1011±239 kcal, respectively). The energy ingested derived from each macronutrient and self-reported appetite remained unchanged. Although the amplitudes of the P3b component evoked by food and non-food visual stimuli were not significantly different during CON, the response to food cues was significantly reduced compared with non-food stimuli after exercise (P<0.01).

Discussion:

An acute exercise favors decreased neural response to food cues compared with non-food ones in obese adolescents that may contribute to their subsequently reduced energy intake.

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Acknowledgements

The authors are grateful to the French Nestlé Foundation who supported this study through its 2013 Research Grant. We also want to particularly thank the Dr SEROG Patrick for his huge help and support and all the adolescents who took part in the study.

Author information

Authors and Affiliations

  1. Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA

    S N Fearnbach & K L Keller

  2. Clermont Université, Université Blaise Pascal, Laboratoire de Psychologie Sociale et Cognitive, Clermont-Ferrand, France

    L Silvert

  3. CNRS, UMR 6024, LAPSCO, Clermont-Ferrand, France

    L Silvert

  4. Department of Food Science, The Pennsylvania State University, University Park, PA, USA

    K L Keller

  5. Clermont Auvergne University, EA 3533, Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont-Ferrand, France

    P M Genin & D Thivel

  6. INRA, UMR 1397, Laboratoire CarMeN, INSERM U1060, Université Lyon 1, INSA de Lyon, Université Lyon-Sud Rockefeller et Charles Merieux, Lyon, France

    B Morio

  7. Clermont-Ferrand University Hospital, Biostatistics unit (DRCI), Clermont-Ferrand, France

    B Pereira

  8. Department of Sport Medicine and Functional Explorations, Clermont-Ferrand University Hospital, G. Montpied Hospital, Clermont-Ferrand, France

    M Duclos

  9. INRA, UMR 1019, Clermont-Ferrand, France

    M Duclos & Y Boirie

  10. CRNH-Auvergne, Clermont-Ferrand, France

    M Duclos, Y Boirie & D Thivel

  11. Department of Human Nutriton, Clermont-Ferrand University Hospital, G. Montpied Hospital, Clermont-Ferrand, France

    Y Boirie

  12. University Clermont 1, UFR Medicine, Clermont-Ferrand, France

    Y Boirie

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  1. S N Fearnbach
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  2. L Silvert
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Correspondence to D Thivel.

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Fearnbach, S., Silvert, L., Keller, K. et al. Reduced neural response to food cues following exercise is accompanied by decreased energy intake in obese adolescents. Int J Obes 40, 77–83 (2016). https://doi.org/10.1038/ijo.2015.215

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  • DOI: https://doi.org/10.1038/ijo.2015.215

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