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Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study

International Journal of Obesity volume 32, pages S21–S24 (2008)Cite this article

Abstract

Objective:

The metabolic syndrome is associated with increased risk for cardiovascular disease and diabetes. Several analyses from the Atherosclerosis Risk in Communities (ARIC) study have been performed to examine the role of the metabolic syndrome and its components in predicting risk for cardiovascular disease and diabetes.

Design and subjects:

The large, biracial, population-based ARIC study enrolled 15 792 middle-aged Americans in four communities in the United States and has followed them for the development of cardiovascular disease and diabetes.

Measurements:

Outcome parameters included prevalence of the metabolic syndrome and its individual components, carotid intima-media thickness, incident coronary heart disease, incident ischemic stroke and incident diabetes.

Results and conclusion:

Several analyses from the ARIC study have shown that the metabolic syndrome, as well as individual metabolic syndrome components, is predictive of the prevalence and incidence of coronary heart disease, ischemic stroke, carotid artery disease and diabetes.

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Acknowledgements

The Atherosclerosis Risk in Communities Study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021 and N01-HC-55022. Additional funding for this study was provided by National Institute of Diabetes and Digestive and Kidney Diseases Grant RO1-DK56918. We thank the staff and participants of the ARIC study for their important contributions.

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Authors and Affiliations

  1. Department of Medicine, Section of Atherosclerosis and Vascular Medicine, Baylor College of Medicine, Houston, TX, USA

    C M Ballantyne & R C Hoogeveen

  2. Center for Cardiovascular Disease Prevention, Methodist DeBakey Heart Center, Houston, TX, USA

    C M Ballantyne & R C Hoogeveen

  3. Department of Epidemiology, Merck Research Labs, North Wales, PA, USA

    A M McNeill

  4. Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA

    A M McNeill, G Heiss, M I Schmidt & B B Duncan

  5. Graduate Studies Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

    M I Schmidt & B B Duncan

  6. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA

    J S Pankow

Authors
  1. C M Ballantyne
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  2. R C Hoogeveen
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  3. A M McNeill
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  4. G Heiss
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  5. M I Schmidt
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  6. B B Duncan
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  7. J S Pankow
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Corresponding author

Correspondence to C M Ballantyne.

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Ballantyne, C., Hoogeveen, R., McNeill, A. et al. Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study. Int J Obes 32 (Suppl 2), S21–S24 (2008). https://doi.org/10.1038/ijo.2008.31

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