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Impact of erectile function and age in men with lower urinary tract symptoms on ejaculatory dysfunction and premature ejaculation

Abstract

Lower urinary tract symptoms (LUTSs) and ED are clearly correlated, but to date no correlation with ejaculatory dysfunction (EjD) has been identified. Therefore, this study evaluated the impact of erectile function in men with LUTS on EjD and premature ejaculation (PE). Erectile function, PE and EjD of 239 men (mean age, 53.0±10.65 years), International Prostate Symptom Score (IPSS), International Index of Erection Function (IIEF), intravaginal ejaculatory latency time (IELT) and the seven-item Male Sexual Health questionnaire (MSHQ)-EjD were used to compare with the degree of LUTS. Ages were divided into five groups (<40, 40–49, 50–59, 60–69 and >70 years). The IPSS categorized patients into three symptom groups: mild, 1–7; moderate, 8–19; and severe, >19. ED was classified into five categories based on IIEF-EF scores: severe (0–6), moderate (7–12), mild-to-moderate (13–18), mild (19–24) and normal (25–30). The correlations among age, IIEF-EF, IELT and the MSHQ-EjD domain were studied through regression and cross-tabulation analyses. The results revealed that aging significantly affected each item of the MSHQ-EjD (P<0.05). The IIEF-EF domain was also correlated with each question on the MSHQ-EjD (P<0.05). PE (IELT <1 min) increased in incidence as patients got older but was not linked to IIEF-EF (P>0.05). These results indicate that EjD is closely related to age and erectile function, and that PE is closely related to age, although PE is not related to erectile function.

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References

  1. Giuliano F . Lower urinary tract symptoms and sexual dysfunction: a common approach. BJU Int 2008; 101: 22–26.

    Article  CAS  Google Scholar 

  2. Jung JH, Jae SU, Kam SC, Hyun JS . Correlation between lower urinary tract symptoms (LUTS) and sexual function in benign prostatic hyperplasia: impact of treatment of LUTS on sexual function. J Sex Med 2009; 6: 2299–2304.

    Article  Google Scholar 

  3. Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E et al. Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol 2003; 44: 637–649.

    Article  Google Scholar 

  4. Giuliano F, Clement P . Neuroanatomy and physiology of ejaculation. Annu Rev Sex Res 2005; 16: 190–216.

    PubMed  Google Scholar 

  5. Allard J, Truitt WA, McKenna KE, Coolen LM . Spinal cord control of ejaculation. World J Urol 2005; 23: 119–126.

    Article  Google Scholar 

  6. Blanker MH, Bosch JL, Groeneveld FP, Bohnen AM, Prins A, Thomas S et al. Erectile and ejaculatory dysfunction in a community-based sample of men 50 to 78 years old: prevalence, concern, and relation to sexual activity. Urology 2001; 57: 763–768.

    Article  CAS  Google Scholar 

  7. Blanker MH, Bohnen AM, Groeneveld FP, Bernsen RM, Prins A, Thomas S et al. Correlates for erectile and ejaculatory dysfunction in older Dutch men: a community-based study. J Am Geriatr Soc 2001; 49: 436–442.

    Article  CAS  Google Scholar 

  8. Chung WS, Nehra A, Jacobson DJ, Roberts RO, Rhodes T, Girman CJ et al. Lower urinary tract symptoms and sexual dysfunction in community-dwelling men. Mayo Clin Proc 2004; 79: 745–749.

    Article  Google Scholar 

  9. Li MK, Garcia LA, Rosen R . Lower urinary tract symptoms and male sexual dysfunction in Asia: a survey of ageing men from five Asian countries. BJU Int 2005; 96: 1339–1354.

    Article  Google Scholar 

  10. Tang WS, Khoo EM . Prevalence and correlates of premature ejaculation in a primary care setting: a preliminary cross-sectional study. J Sex Med 2011; 8: 2071–2078.

    Article  Google Scholar 

  11. Gutman S, Merrick GS, Butler WM, Wallner KE, Allen Z, Galbreath RW et al. Severity categories of the International Prostate Symptom Score before, and urinary morbidity after, permanent prostate brachytherapy. BJU Int 2006; 97: 62–68.

    Article  Google Scholar 

  12. Ahmed HU, Freeman A, Kirkham A, Sahu M, Scott R, Allen C et al. Focal therapy for localized prostate cancer: a phase I/II trial. J Urol 2011; 185: 1246–1254.

    Article  CAS  Google Scholar 

  13. Rosen RC, Catania J, Pollack L, Althof S, O’Leary M, Seftel AD . Male Sexual Health Questionnaire (MSHQ): scale development and psychometric validation. Urology 2004; 64: 777–782.

    Article  Google Scholar 

  14. McMahon CG, Althof SE, Waldinger MD, Porst H, Dean J, Sharlip ID et al. An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation. J Sex Med 2008; 5: 1590–1606.

    Article  Google Scholar 

  15. Laumann EO, Nicolosi A, Glasser DB, Paik A, Gingell C, Moreira E et al. Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impotence Res 2005; 17: 39–57.

    Article  CAS  Google Scholar 

  16. Nicolosi A, Laumann E, Glaser D, Moreira E, Paik A, Gingell C . Global study of sexual attitudes and behaviors investigator's group. Sexual behavior and sexual dysfunctions after age 40: the global study of sexual attitudes and behaviors. Urology 2004; 64: 991–997.

    Article  Google Scholar 

  17. Althof SE, Abdo CH, Dean J, Hackett G, McCabe M, McMahon CG et al. International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation. J Sex Med 2010; 7: 2947–2969.

    Article  Google Scholar 

  18. Jaspersen-Gastelum J, Rodríguez JA, Espinosa de los Monteros FJ, Beas-Sandoval L, Guzmán-Esquivel J, Calvo DD et al. Prostatic profile, premature ejaculation, erectile function and andropause in an at-risk Mexican population. Int Urol Nephrol 2009; 41: 303–312.

    Article  CAS  Google Scholar 

  19. Porst H, Montorsi F, Rosen RC, Gaynor L, Grupe S, Alexander J . The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Eur Urol 2007; 51: 816–823.

    Article  Google Scholar 

  20. Basile Fasolo C, Mirone V, Gentile V, Parazzini F, Ricci E . Premature ejaculation: prevalence and associated conditions in a sample of 12,558 men attending the andrology prevention week 2001—a study of the Italian Society of Andrology (SIA). J Sex Med 2005; 2: 376–382.

    Article  CAS  Google Scholar 

  21. Ahn TY, Park JK, Lee SW, Hong JH, Park NC, Kim JJ et al. Prevalence and risk factors for erectile dysfunction in Korean men: results of an epidemiological study. J Sex Med 2007; 4: 1269–1276.

    Article  Google Scholar 

  22. Tubaroa A, Politob M, Giambronic L, Famularid C, Gangee E, Ostardo E et al. Sexual function in patients with LUTS suggestive of BPH. Eur Urol 2001; 40: 19–22.

    Article  Google Scholar 

  23. Frankel SJ, Donovan JL, Peters TI, Abrams P, Dabhoiwala NF, Osawa A et al. Sexual dysfunction in men with lower urinary tract symptoms. J Clin Epidemiol 1998; 51: 677–685.

    Article  CAS  Google Scholar 

  24. Rosen RC, Fitzpatrick JM . Ejaculatory dysfunction in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. BJU Int 2009; 104: 974–983.

    Article  Google Scholar 

  25. Wein AJ, Coyne KS, Tubaro A, Sexton CC, Kopp ZS, Aiyer LP . The impact of lower urinary tract symptoms on male sexual health: EpiLUTS. BJU Int 2009; 103: 33–41.

    Article  Google Scholar 

  26. Başar MM, Yilmaz E, Ferhat M, Başar H, Batislam E . Terazosin in the treatment of premature ejaculation: a short-term follow-up. Int Urol Nephrol 2005; 37: 773–777.

    Article  Google Scholar 

  27. Jannini EA, McMahon C, Chen J, Aversa A, Perelman M . The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculation. J Sex Med 2011; 8: 2135–2143.

    Article  Google Scholar 

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Correspondence to J S Hyun.

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Hwa, J., Kam, S., Choi, J. et al. Impact of erectile function and age in men with lower urinary tract symptoms on ejaculatory dysfunction and premature ejaculation. Int J Impot Res 24, 101–105 (2012). https://doi.org/10.1038/ijir.2012.1

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