Abstract
The prospects for mapping genes conferring susceptibility to common disorders such as age-related maculopathy have increased as a result of advances in high-throughput genotyping using single nucleotide polymorphisms. This should not obscure the magnitude of the task of identifying what are potentially a diverse group of genetic variants with small or intermediate effects on disease susceptibility. Strategies for increasing the odds of success in such an endeavour are discussed.
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Wright, A. Strategies for mapping susceptibility genes in age-related maculopathy. Eye 15, 401–406 (2001). https://doi.org/10.1038/eye.2001.144
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DOI: https://doi.org/10.1038/eye.2001.144
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