Abstract
Retinopathy of prematurity (ROP) continues to be a problem for some preterm infants who survive the neonatal period. We review changes which have occurred in the premature infant population and methods of ophthalmological examination since the last survey of ROP in the United Kingdom was conducted between 1951 and 1953. We have analysed data from a retrospective study, and from our current prospective survey of ROP in the East Midlands, to determine the age at onset of acute ROP. The results show that the ophthalmoscopically visible signs of ROP develop over a narrow postmenstrual age range suggesting that acute ROP occurs only after the retina and/or its vasculature have reached a certain stage of development.
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References
Alberman ED : Epidemiology of Retinopathy of Prematurity. In: Silverman WA, Flynn JT eds. Contemporary issues in Fetal and Neonatal Medi-cine 2 Retinopathy of Prematurity. Oxford: Blackwell Scientific Publications 1985; 249–66.
Crosse VM : The problem of retrolental fibroplasia in the city of Birmingham. Trans. Ophthalmol. Soc. UK. 1951; 71: 609–12.
Campbell K : Intensive oxygen therapy as a possible cause of retrolental fibroplasia: a clinical approach. Med. J. Aust. 1951; 2: 48–50.
Report to the Medical Research Council by their conference on retrolental fibroplasia: Retrolental Fibroplasia in the United Kingdom. Br. Med. J. 1955; 2: 78–82.
Kinsey VE : Retrolental fibroplasia: a cooperative study of retrolental fibroplasia and the use of oxygen. Arch. Ophthalmol. 1956; 56: 481–529.
Ashton N, Ward B, Serpell G : Role of oxygen in the genesis of retrolental fibroplasia A preliminary report. Br. J. Ophthalmol. 1953; 37: 513–20.
Sorsby A : The incidence and causes of blindness in England and Wales 1948-1962. Reports in Public Health and Medical Subjects no. 114. HMSO 1966.
Cross KW : Cost of preventing retrolental fibroplasia? Lancet 1973; 2: 954–6.
Silverman WA : Retrolental fibroplasia: a modern parable. Monographs in Neonatology. New York: Grune and Stratton, 1980.
Gunn TR, Aranda JV, Little J : Incidence of retrolental fibroplasia. Lancet 1978; 1: 216–7.
McCormick AQ : Retinopathy of prematurity. Curr. Probl. Pediatr. 1977; 7: 3–28.
Phelps DL : Retinopathy of prematurity: An estimate of vision loss in the United States 1979. Pediatrics 1981; 67: 924–5.
Lucey JF, Dangman B : A reexamination of the role of oxygen in retrolental fibroplasia. Pediatrics 1984; 73: 82–96.
Aranda JV, Sweet AY : Sustained hyperoxemia without cicatricial retrolental fibroplasia. Pediatrics 1974; 54: 434–7.
Kushner BJ, Gloeckner E : Retrolental fibroplasia in full term infants without exposure to supplemental oxygen. Am. J. Ophthalmol. 1984; 97: 148–53.
Adamkin DH, Shott RJ, Cook LN, Andrews BF : Nonhyperoxic retrolental fibroplasia. Pediatrics 1977; 60: 828–30.
Pharoah POD, Alberman ED : Mortality of low birthweight infants in England and Wales 1953 to 1979. Arch. Dis. Child. 1981; 56: 86–9.
Boyd JT, Hirst KM : Incidence of retrolental fibroplasia in England and Wales in 1951. Br. Med. J. 1955; 2: 83–5.
Kinsey VE et al.: PaO2 levels and retrolental fibroplasia: A report of the cooperative study. Pediatrics 1977; 60: 655–67.
Mushin AS : Retinopathy of prematurity—A disease of increasing incidence? Trans. Ophthalmol. Soc. UK. 1974; 94: 251–7.
Blindness and Partial Sight in England 1969-1976: Reports on Public Health and Medical Subjects no. 129 HMSO.
An international classification of retinopathy of prematurity. Br. J. Ophthalmol 1984; 68: 690–7.
Fielder AR, Ng YK, Levene MI : Retinopathy of prematurity: age at onset. Arch. Dis. Child. 1986; 61: 774–8.
Dubowitz LMS, Dubowitz V, Goldberg C : Clinical assessment of gestational age in the newborn infant. J. Pediatr. 1970; 77: 1–10.
Silverman WA, Blodi FC, Locke JC, Day RL, Reese AB : Incidence of retrolental fibroplasia in a New York nursery. Arch. Ophthalmol. 1952; 48: 698–711.
Flynn JT : Discussion on article by Palmer EA: ‘Optimal timing of examination for acute retrolental fibroplasia’. Ophthalmology 1981; 88: 667–8.
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Ng, Y., Fielder, A. & Levene, M. Retinopathy of prematurity in the United Kingdom. Eye 1, 386–390 (1987). https://doi.org/10.1038/eye.1987.58
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DOI: https://doi.org/10.1038/eye.1987.58
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