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  • RESEARCH HIGHLIGHT

A single day on a fatty diet gives the gut a makeover

A mouse’s intestines undergo changes in gene activity and cellular proliferation within 24 hours of starting on high-fat food.
A composite of two images showing the fat absorption in the intestines of a mouse - this is shown in green

The intestinal lining (left) of a mouse on day one of a high-fat diet show much less lipid absorption (green) than on day seven of the diet (right). Credit: Jacob Ryan Enriquez

Just one day of a high-fat diet is all that it takes to cause stress in the gut, at least in mice1.

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Nature 611, 639 (2022)

doi: https://doi.org/10.1038/d41586-022-03707-3

References

  1. Enriquez, J. R. et al. Cell Rep. 41, 111641 (2022).

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