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References
Hannemann F, Bichet A, Ewen KM, Bernhardt R . Cytochrome P450 systems-biological variations of electron transport chains. Biochim Biophys Acta 2007; 1770: 330–344.
Winqvist O, Karlsson FA, Kampe O . 21-Hydroxylase, a major autoantigen in idiopathic Addison's disease. Lancet 1992; 339: 1559–1562.
Bogdanos DP, Invernizzi P, Mackay IR, Vergani D . Autoimmune liver serology: current diagnostic and clinical challenges. World J Gastroenterol 2008; 14: 3374–3387.
Dalekos GN, Zachou K, Liaskos C, Gatselis N . Autoantibodies and defined target autoantigens in autoimmune hepatitis: an overview. Eur J Int Med 2002; 13: 293–303.
Downie D, McFadyen MC, Rooney PH, Cruickshank ME, Parkin DE, Miller ID et al. Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers. Clin Cancer Res 2005; 11: 7369–7375.
Rieger MA, Ebner R, Bell DR, Kiessling A, Rohayem J, Schmitz M et al. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. Cancer Res 2004; 64: 2357–2364.
Zöllner A, Dragan CA, Pistorius D, Muller R, Bode HB, Peters FT et al. Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. Biol Chem 2009; 390: 313–317.
Yang X, Hutter M, Goh WW, Bureik M . CYP4Z1—A human cytochrome P450 enzyme that might hold the key to curing breast cancer. Curr Pharm Des; e-pub ahead of print 7 February 2017; doi:10.2174/1381612823666170207150156.
Stadler V, Felgenhauer T, Beyer M, Fernandez S, Leibe K, Guttler S et al. Combinatorial synthesis of peptide arrays with a laser printer. Angew Chem Int Ed Engl 2008; 47: 7132–7135.
Acknowledgements
We are grateful to Feng Yu-Mei from the Department of Biochemistry and Molecular Biology at Tianjin Medical University Cancer Institute and Hospital (Tianjin, China) for providing cancer patient sera and to Zhang Weiying from the Institute of Molecular Biology at Nankai University (Tianjin, China) for providing MCF-7 cells.
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Nunna, V., Jalal, N. & Bureik, M. Anti-CYP4Z1 autoantibodies detected in breast cancer patients. Cell Mol Immunol 14, 572–574 (2017). https://doi.org/10.1038/cmi.2017.21
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DOI: https://doi.org/10.1038/cmi.2017.21
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