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References
Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kobayashi T et al. Cardiovascular toxicity of cryopreserved cord blood cell infusion. Bone Marrow Transplant 2008; 41: 861–865.
Barker JN, Abboud M, Rice RD, Hawke R, Schaible A, Heller G et al. A 'no-wash' albumin-dextran dilution strategy for cord blood unit thaw: high rate of engraftment and a low incidence of serious infusion reactions. Biol Blood Marrow Transplant 2009; 15: 1596–1602.
Hahn T, Bunworasate U, George MC, Bir AS, Chinratanalab W, Alam AR et al. Use of nonvolume-reduced (unmanipulated after thawing) umbilical cord blood stem cells for allogeneic transplantation results in safe engraftment. Bone Marrow Transplant 2003; 32: 145–150.
Bear AS, Hanley PJ, Bosque DM, Cruz CR, Kaur I, Liu H et al. Low rate of infusional toxicity after expanded cord blood transfusion. Cytotherapy 2014; 16: 1153–1157.
Choi S, Hoffmann S, Cooling L . Another case of acute cardiopulmonary toxicity with cord blood infusion: is dextran the culprit? Transfusion 2012; 52: 207–208.
Hatano K, Fujiwara S, Kishino K, Nagamura-Inoue T, Muroi K . Anaphylaxis associated with cord blood infusion. Jpn J Transfus Cell Ther 2014; 60: 513–514.
Ma RW, Kwan JM, Ma DD, Fay KC . Acute life-threatening cardiovascular toxicity with umbilical cord blood transfusion: the role of dextran. Am J Hematol 2010; 85: 722–724.
Miller JP. A centralized cord blood registry to facilitate allogenic, unrelated cord blood transplantation, BB-IND #7555 safety report. National Marrow Donor Program: Minneapolis, MN, USA, 2009.
Petropoulou AD, Bellochine R, Norol F, Marie J-P, Rio B . Coronary artery spasm after infusion of cryopreserved cord blood cells. Bone Marrow Transplant 2007; 40: 397–398.
Cooling L, Gorlin JB. Transfusion reactions associated with hematopoietic progenitor cell reinfusion. In: Popovsk MA (ed). Transfusion Reactions, 4th edn. AABB Press: Bethseda, MD, USA, 2012.
Zingerman CE, Landow L, Wise RP . Anaphylactoid reactions to dextran 40 and 70: reports to the United States Food and Drug Administration, 1969-2004. J Vasc Surg 2006; 43: 1004–1009.
Ljungstrom KG . Dextran 40 therapy made safer by pretreatment with dextran 1. Plast Reconstr Surg 2007; 120: 337–340.
Reich-Slotky R, Bachegowda LS, Ancharski M, Mendeleyeva L, Rubinstein P, Rennert H et al. How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions. Transfusion 2015; 55: 1147–1153.
Cloutier M, Simard C, Jobin C, Fournier D, Neron S . An alternative to dextran for the thawing of cord blood units. Transfusion 2016; 56: 1786–1791.
Kleinman S, chan P, Robillard P . Risks associated with transfusion of cellular blood components in Canada. Transfus Med Rev 2003; 17: 120–162.
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Cooling, L., Sankar, A., Mody, R. et al. A severe umbilical cord stem cell infusion reaction due to dextran in an atopic pediatric patient. Bone Marrow Transplant 52, 1051–1053 (2017). https://doi.org/10.1038/bmt.2017.33
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DOI: https://doi.org/10.1038/bmt.2017.33
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