Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter to the Editor
  • Published:

Pre-transplant diastolic but not systolic dysfunction has a negative prognostic impact after allogeneic stem cell transplantation

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1

References

  1. Ljungman P, Brand R, Hoek J, de la Camara R, Cordonnier C, Einsele H et al. Donor cytomegalovirus status influences the outcome of allogeneic stem cell transplant: a study by the European group for blood and marrow transplantation. Clin Infect Dis 2014; 59: 473–481.

    Article  Google Scholar 

  2. Luskin MR, Heil DS, Tan KS, Choi S, Stadtmauer EA, Schuster SJ et al. The Impact of EBV status on characteristics and outcomes of posttransplantation lymphoproliferative disorder. Am J Transplant 2015; 15: 2665–2673.

    Article  CAS  Google Scholar 

  3. Sorror M . Impacts of pre transplant comorbidities on allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2009; 15: 149–153.

    Article  Google Scholar 

  4. Gratwohl A . The EBMT risk score. Bone Marrow Transplant 2012; 47: 749–756.

    Article  CAS  Google Scholar 

  5. Braverman AC, Antin JH, Plappert MT, Cook EF, Lee RT . Cyclophosphamide cardiotoxicity in bone marrow transplantation: a prospective evaluation of new dose regimens. J Clin Oncol 1991; 9: 1215–1223.

    Article  CAS  Google Scholar 

  6. Voigt JU, Pedrizzetti G, Lysyansky P, Marwick TH, Houle H, Baumann R et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J Cardiovasc Imaging 2015; 16: 1–11.

    Article  CAS  Google Scholar 

  7. Coghlan JG, Handler CE, Kottaridis PD . Cardiac assessment of patients for hematopoietic stem cell transplantation. Best Pract Res Clin Haematol 2007; 20: 247–263.

    Article  CAS  Google Scholar 

  8. Miniati I, Conforti ML, Bernardo P, Tyndall A, Gensini GF, Matucci-Cerinic M . Hematopoietic stem cell transplantation in autoimmune diseases algorithm for cardiovascular assessment. Herz 2007; 32: 43–50.

    Article  Google Scholar 

  9. Coghlan JG, Handler CE, Kottaridis PD . Cardiac assessment of patients for haematopoietic stem cell transplantation. Best Pract Res Clin Haematol. 2007; 20: 247–263.

    Article  CAS  Google Scholar 

  10. Kovács Á, Papp Z, Nagy L . Causes and pathophysiology of heart failure with preserved ejection fraction. Heart Fail Clin 2014; 10: 389–398.

    Article  Google Scholar 

  11. Hurley P, Konety S, Cao Q, Weisdorf D, Blaes A . Hematopoietic stem cell transplantation in patients with systolic dysfunction: can it be done? Biol Blood Marrow Transplant 2015; 21: 300–304.

    Article  Google Scholar 

  12. Kalay N, Basar E, Ozdogru ErO, Cetinkaya I, Dogan A et al. Protective effects of carvedilol against anthracycline-induced cardiomyopathy. J Am Coll Cardiol 2006; 48: 2258–2262.

    Article  CAS  Google Scholar 

  13. Blaes AH, Gaillard P, Peterson BA, Yee D, Virnig D . Angiotensin converting enzyme inhibitors may be protective against cardiac complications following anthracycline chemotherapy. Breast Cancer Res Treat 2010; 122: 585–590.

    Article  CAS  Google Scholar 

  14. Cardinale D, Bacchiani G, Beggiato M, Colombo A, Cipolla CM . Strategies to prevent and treat cardiovascular risk in cancer patients. Semin Oncol 2013; 40: 186–198.

    Article  CAS  Google Scholar 

  15. Bosch X, Rovira M, Sitges M, Domènech A, Ortiz-Pérez JT, de Caralt TM et al. Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submitted to intensive ChemOtherapy for the treatment of Malignant hEmopathies). J Am Coll Cardiol 2013; 61: 2355–2362.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M Sarmiento.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sarmiento, M., Parody, R., Márquez-Malaver, F. et al. Pre-transplant diastolic but not systolic dysfunction has a negative prognostic impact after allogeneic stem cell transplantation. Bone Marrow Transplant 51, 863–865 (2016). https://doi.org/10.1038/bmt.2016.8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/bmt.2016.8

This article is cited by

Search

Quick links