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  • Experimental Oncology
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Genetic evidence that placental site trophoblastic tumours can originate from a hydatidiform mole or a normal conceptus

British Journal of Cancer volume 65, pages 355–358 (1992)Cite this article

Abstract

The genetic origin of two placental site trophoblastic tumours was established using a Y chromosome-specific and locus-specific minisatellite probes. A gestational origin was confirmed for both tumours. In one case the origin of the tumour was consistent with derivation from a normal female conceptus while the other was shown to arise from a homozygous complete hydatidiform mole, an abnormal conceptus more usually associated with the development of choriocarcinoma.

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Authors and Affiliations

  1. Cancer Research Campaign Laboratories, Charing Cross and Westminster Medical School, London, UK

    RA Fisher

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  1. RA Fisher
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  2. FJ Paradinas
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  3. ES Newlands
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  4. GM Boxer
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Fisher, R., Paradinas, F., Newlands, E. et al. Genetic evidence that placental site trophoblastic tumours can originate from a hydatidiform mole or a normal conceptus. Br J Cancer 65, 355–358 (1992). https://doi.org/10.1038/bjc.1992.72

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  • DOI: https://doi.org/10.1038/bjc.1992.72

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