Abstract
Twenty patients with secondary liver tumours, predominantly from colorectal carcinoma, were treated with oral urea at a daily dose of 8 gm-2. Treatment was well tolerated without side-effects. No objective responses were seen. It is concluded that oral urea is ineffective in the treatment of liver metastases from colorectal cancer.
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Clark, P., Slevin, M., Webb, J. et al. Oral urea in the treatment of secondary tumours in the liver. Br J Cancer 57, 317–318 (1988). https://doi.org/10.1038/bjc.1988.70
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DOI: https://doi.org/10.1038/bjc.1988.70