Abstract
Analysis of data from 1434 children with primary renal tumours revealed 57 who developed bone metastases. Of these, 54 were initially recorded as nephroblastoma. Fifty-two of the 57 cases were reviewed histologically, and only 18 were found to be Wilms' tumours. Twenty-three were classified as "Bone-Metastasizing Renal Tumour of Childhood" (BMRTC), and a high male incidence was found for these tumours (M:F=6.7:1). Differences in the pattern of metastasis and the one-year survival between BMRTC and nephroblastoma are discussed. The rarity of bone metastases from true Wilms' tumours is emphasized.
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Marsden, H., Lennox, E., Lawler, W. et al. Bone metastases in childhood renal tumours. Br J Cancer 41, 875–879 (1980). https://doi.org/10.1038/bjc.1980.163
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DOI: https://doi.org/10.1038/bjc.1980.163
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