Abstract
An immunoadsorbent technique is described whereby tumour-specific antibodies may be isolated. Extracts from normal human lung tissue were pooled and bound to cyanogen bromide activated Sepharose 4B. Antisera raised in rabbits to a variety of extracts from human bronchogenic carcinoma were passed through these immunoadsorbent columns to yield antisera specific for tumour-associated antigens as demonstrated by immunodiffusion and immunoelectrophoresis.
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Watson, R., Smith, A. & Levy, J. The Use of Immunoadsorbent Columns for the Isolation of Antibodies Specific for Antigens Associated with Human Bronchogenic Carcinoma. Br J Cancer 29, 183–188 (1974). https://doi.org/10.1038/bjc.1974.57
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DOI: https://doi.org/10.1038/bjc.1974.57
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