Abstract
Electron-microscopic examination of an oat-cell carcinoma associated with the ectopic ACTH syndrome demonstrated characteristic cytoplasmic granules of 60-240 nm. diameter, consisting of a dense central core separated by a clear halo from an outer investing membrane. Comparison with previously examined non-secretory oat-cell carcinomas showed the granules to be more numerous in the present case. They are considered to represent secretory activity in the tumour.
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Corrin, B., McMillan, M. Fine Structure of an Oat Cell Carcinoma of the Lung Associated with Ectopic ACTH Syndrome. Br J Cancer 24, 755–758 (1970). https://doi.org/10.1038/bjc.1970.90
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DOI: https://doi.org/10.1038/bjc.1970.90
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