Letter to the Editor

Breath Testing Consensus Guidelines for SIBO: RES IPSA LOCQUITOR

  • The American Journal of Gastroenterology (2017) 112, 18881889 (2017)
  • doi:10.1038/ajg.2017.233
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    , , et al. Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus. Am J Gastroenterol 2017;112:775–784.

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    , , . Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls. Am J Gastroenterol 2008;103:958–963.

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    , , . Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS. Gut 2011;60:334–340.

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    , . Scintigraphy demonstrates high rate of false-positive results from glucose breath tests for small bowel bacterial over growth. Clin Gastroenterol Hepatol 2016;14:203–208.

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    , , et al. Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbable carbohydrate. Gut 1985;26:834–842.

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    , , et al. The lactulose breath hydrogen test and small intestinal bacterial overgrowth. Am J Gastroenterol 1996;91:1795–1803.

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Author information


  1. Gastrointestinal Diseases Research Unit (GIDRU), Kingston General Hospital, Queen's University, Kingston, Ontario, Canada

    • William Paterson
    •  & Stephen J Vanner
  2. Department of Medicine, Pharmacology, and Physiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

    • Michael Camilleri
  3. Department of Internal Medicine & Clinical Nutrition, University of Gothenburg, Gothenburg, Sweden

    • Magnus Simren
  4. Division of Gastroenterology, University Hospital Leuven, Leuven, Belgium

    • Guy Boeckxstaens


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Competing interests

Guarantor of the article: Stephen J. Vanner, MD.

Specific author contributions: All authors contributed to the content of the letter and approved the final draft.

Financial support: None.

Potential competing interests: None.

Corresponding author

Correspondence to Stephen J Vanner.