Abstract
This paper provides the conceptual basis for a modeling logic that is currently being developed in the National Exposure Research Laboratory (NERL) of the U.S. Environmental Protection Agency (EPA) for use in intake dose assessments involving substances that can enter the body via multiple routes of exposure. NERL is simultaneously developing a consolidated human activity database that will provide much of the data needed to parameterize equations used to implement the logic. EPA's Office of Air Quality Planning and Standards (OAQPS) is, in part, using the logic in its on-going review of the carbon monoxide national ambient air quality standard.
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Disclaimer: The information contained in this paper has been funded in part by the U.S. Environmental Protection Agency. It has been subjected to Agency review and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.
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MCCURDY, T. Conceptual basis for multi-route intake dose modeling using an energy expenditure approach. J Expo Sci Environ Epidemiol 10, 86–97 (2000). https://doi.org/10.1038/sj.jea.7500066
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DOI: https://doi.org/10.1038/sj.jea.7500066
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