Abstract
We report that α-tocopheryl succinate, a vitamin E analogue with pro-apoptotic properties, selectively kills cells with a malignant or transformed phenotype, i.e. multiple haematopoietic and carcinoma cell lines, while being non-toxic to normal, i.e. primary and non-transformed cells. These findings strongly suggest a potential of this micronutrient in the therapy and/or prevention of cancer without significant side-effects. © 2001 Cancer Research Campaign
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16 November 2011
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From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
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Neuzil, J., Weber, T., Gellert, N. et al. Selective cancer cell killing by α-tocopheryl succinate. Br J Cancer 84, 87–89 (2001). https://doi.org/10.1054/bjoc.2000.1559
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DOI: https://doi.org/10.1054/bjoc.2000.1559
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