Abstract
Some studies suggest that Asian children with leukaemia have a worse outcome than Whites. Survival of Asians with ALL treated at the Birmingham Children’s Hospital from 1975 to 1994 was the same as that of Whites, despite their greater deprivation and poorer nutrition. For one 5-year period (1980–1984) Asians had significantly poorer survival, even after adjustment for prognostic factors. Poor treatment compliance during that period may have contributed to this difference. © 2000 Cancer Research Campaign
Similar content being viewed by others
Article PDF
Change history
16 November 2011
This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication
References
Altman DG (1991) Practical Statistics for Medical Research, Chapman and Hall: London
Borato Viana M, Murao M, Ramos G, Oliviera HM, de Carvalho RI, de Bastos M, Colosimo EA and Silvestrini WG (1994) Malnutrition as a prognostic factor in lymphoblastic leukaemia: a multivariate analysis. Arch Dis Child 71: 304–310
Burnet AK and Eden OB (1997) The treatment of acute leukaemia. Lancet 349: 270–275
Cole TJ, Freeman JV and Preece MA (1995) Body mass index reference curves for the UK, 1990. Arch Dis Child 73: 25–29
Kalwinsky DK, Rivera G, Dahl GV, Roberson P, George S, Murphy SB and Simone JV (1985) Variation by race in presenting clinical and biological features of childhood acute lymphoblastic leukaemia: implications for treatment outcome. Leuk Res 9: 817–823
Lobato-Mendizabal E, Ruiz-Arguelles GJ and Marin-Lopez A (1989) Leukaemia and nutrition I: malnutrition is an adverse prognostic factor in the outcome of treatment of patients with standard-risk acute lymphoblastic leukaemia. Leuk Res 13: 899–906
McKinney PA, Feltbower RG, Parslow RC, Lewis IJ, Picton S, Kinsey SE and Bailey CC (1999) Survival from childhood cancer in Yorkshire, UK: effect of ethnicity and socio-economic status. Eur J Cancer 35: 1816–1823
Oakhill A and Mann JR (1983) Poor prognosis of acute lymphoblastic leukaemia in Asian children living in the United Kingdom. Br Med J 286: 839–841
OPCS (Office of Population Censuses and Surveys) (1993) 1991 Census Report for England: Regional Health Authorities. HMSO: London
Pinkel D (1995) Acute lymphoid leukaemia outcomes in black and white children (letter). JAMA 274: 379–380
Pui CH, Boyett JM, Hancock ML, Pratt CB, Meyer WH and Crist WM (1995) Outcome of treatment for childhood cancer in black as compared with white children. JAMA 273: 633–637
Rona RJ and Chinn S (1986) National Study on Health and Growth: social and biological factors associated with height of children from ethnic groups living in England. Ann Hum Biol 13: 453–471
Rothwell D (1982) Duration of chemotherapy in childhood acute lymphoblastic leukaemia. Med Pediatr Oncol 10: 511–520
Townsend P, Phillimore P and Beattie A (1988) Health and Deprivation. Inequality and the North, Croom Helm: London
Walters TR, Bushmore M and Simone J (1972) Poor prognosis in negro children with acute lymphoblastic leukaemia. Cancer 29: 210–214
Weir J, Reilly JJ, McColl JH and Gibson BES (1998) No evidence for an effect of nutritional status at diagnosis on prognosis in children with acute lymphoblastic leukaemia. J Paediatr Hematol Oncol 20: 534–538
Author information
Authors and Affiliations
Rights and permissions
From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
About this article
Cite this article
Powell, J., Mendez, E., Parkes, S. et al. Factors affecting survival in White and Asian children with acute lymphoblastic leukaemia. Br J Cancer 82, 1568–1570 (2000). https://doi.org/10.1054/bjoc.1999.1080
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1054/bjoc.1999.1080
Keywords
This article is cited by
-
Socio-economic and ethnic disparities in childhood cancer survival, Yorkshire, UK
British Journal of Cancer (2023)
-
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia
Nature Genetics (2011)