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Cytochrome P450 3A pharmacogenetics: the road that needs traveled

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References

  1. Shimada T et al. J Pharmacol Exp Ther 1994; 270: 414–423.

  2. Kolars JC et al. J Clin Invest 1992; 90: 1871–1878.

  3. Wilkinson GR . J Pharmacokinet Biopharm 1996; 24: 475–490.

  4. Benet LZ et al. 1996: 3–27.

  5. Watkins PB . Pharmacogenetics 1994; 4: 171–184.

  6. Ball SE et al. Clin Pharmacol Ther 1999; 66: 288–294.

  7. von Moltke LL et al. J Clin Pharmacol 2000; 40: 200–204.

  8. Westlind A et al. Biochem Biophys Res Commun 2001; 281: 1349–1355.

  9. Finta C, Zaphiropoulos PG . Gene 2000; 260: 13–23.

  10. Eiselt R et al. Pharmacogenetics 2001; 11: 447–458.

  11. Ozdemir V et al. Pharmacogenetics 2000; 10: 373–388.

  12. Kuehl P et al. Nat Genet 2001; 27: 383–391.

  13. Burk O et al. J Biol Chem 2002; 277: 24 280–24 288.

  14. Rebbeck TR et al. J Natl Cancer Inst 1998; 90: 1225–1229.

  15. Felix CA et al. Proc Natl Acad Sci USA 1998; 95: 13 176–13 181.

  16. Wrighton SA et al. Mol Pharmacol 1990; 38: 207–213.

  17. Komori M et al. Biochemistry 1990; 29: 4430–4433.

  18. Schuetz JD et al. Pharmacogenetics 1994; 4: 11–20.

  19. Marill J et al. Mol Pharmacol 2000; 58: 1341–1348.

  20. Caraco Y et al. J Pharmacol Exp Ther 1999; 290: 413–422.

  21. Brosen K et al. Eur J Clin Pharmacol 1993; 44: 349–355.

  22. Dalen P et al. Clin Pharmacol Ther 1998; 63: 444–452.

  23. Andersson T et al. Pharmacogenetics 1992; 2: 25–31.

  24. Sohn DR et al. Clin Pharmacol Ther 1997; 61: 574–582.

  25. Furuta T et al. Ann Intern Med 1998; 129: 1027–1030.

  26. Steward DJ et al. Pharmacogenetics 1997; 7: 361–367.

  27. Givens RC et al. Drug Metab Rev 2002; 34: 67 Abst.

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Correspondence to D A Flockhart.

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Flockhart, D., Rae, J. Cytochrome P450 3A pharmacogenetics: the road that needs traveled. Pharmacogenomics J 3, 3–5 (2003). https://doi.org/10.1038/sj.tpj.6500144

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