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Neurodegeneration

An expansion in ALS genetics

Nature volume 466, pages 1052–1053 (2010)Cite this article

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Aggregates and mutations of the proteins ataxin-2 and TDP-43 have been implicated in distinct neurodegenerative disorders. An interplay between these proteins is now reported for amyotrophic lateral sclerosis.

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Figure 1: PolyQ-tract size matters.

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Authors and Affiliations

  1. Clotilde Lagier-Tourenne and Don W. Cleveland are at the Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093-0670, USA. dcleveland@ucsd.edu,

    Clotilde Lagier-Tourenne & Don W. Cleveland

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  1. Clotilde Lagier-Tourenne
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  2. Don W. Cleveland
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Lagier-Tourenne, C., Cleveland, D. An expansion in ALS genetics. Nature 466, 1052–1053 (2010). https://doi.org/10.1038/4661052a

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