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Alzheimer's disease

The latest suspect

Nature volume 454, pages 707–708 (2008)Cite this article

Many genetic mutations and several environmental factors contribute to Alzheimer's disease. Yet another disease risk gene, one that is involved in calcium regulation, has been added to the mix.

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Figure 1: Calcium homeostasis and Alzheimer's disease.

References

  1. Dreses-Werringloer, U. et al. Cell 133, 1149–1161 (2008).

    Article  CAS  Google Scholar 

  2. Bertram, L., McQueen, M. B., Mullin, K., Blacker, D. & Tanzi, R. E. Nature Genet. 39, 17–23 (2007).

    Article  CAS  Google Scholar 

  3. Green, K. N. et al. J. Cell Biol. 181, 1107–1116 (2008).

    Article  CAS  Google Scholar 

  4. Yoo, A. S. et al. Neuron 27, 561–572 (2000).

    Article  CAS  Google Scholar 

  5. Sherrington, R. et al. Nature 375, 754–760 (1995).

    Article  ADS  CAS  Google Scholar 

  6. Levy-Lahad, E. et al. Science 269, 973–977 (1995).

    Article  ADS  CAS  Google Scholar 

  7. Cheung, K.-H. et al. Neuron 58, 871–883 (2008).

    Article  CAS  Google Scholar 

  8. LaFerla, F. M. Nature Rev. Neurosci. 3, 862–872 (2002).

    Article  CAS  Google Scholar 

  9. Bertram, L. et al. Science 290, 2302–2303 (2000).

    Article  ADS  CAS  Google Scholar 

  10. http://www.alzgene.org

  11. Reiman, E. M. et al. Neuron 54, 713–720 (2007).

    Article  CAS  Google Scholar 

  12. Li, H. et al. Arch. Neurol. 65, 45–53 (2008).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Neurology, Rudolph E. Tanzi and Lars Bertram are in the Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease (MIND), Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA. tanzi@helix.mgh.harvard.edu,

    Rudolph E. Tanzi & Lars Bertram

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  1. Rudolph E. Tanzi
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  2. Lars Bertram
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Tanzi, R., Bertram, L. The latest suspect. Nature 454, 707–708 (2008). https://doi.org/10.1038/454706a

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