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Pharmacology

Unready for action

Boy scouts recognize that the key to success is to be prepared. The same is true of molecules that bind to and open ion channels — the least effective ones are slower to prepare the channel to be ready for opening.

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Figure 1: Models for partial agonism.

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Steinbach, J. Unready for action. Nature 454, 704–705 (2008). https://doi.org/10.1038/454704a

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