Boy scouts recognize that the key to success is to be prepared. The same is true of molecules that bind to and open ion channels — the least effective ones are slower to prepare the channel to be ready for opening.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lape, R., Colquhoun, D. & Sivilotti, L. G. Nature 454, 722–727 (2008).
del Castillo, J. & Katz, B. Proc. R. Soc. Lond. B Biol. Sci. 146, 362–368 (1957).
Burzomato, V. et al. J. Neurosci. 24, 10924–10940 (2004).
Bafna, P. A., Purohit, P. G. & Auerbach, A. PLoS ONE 3, e2515 (2008).
Auerbach, A. Proc. Natl Acad. Sci. USA 102, 1408–1412 (2005).
Grosman, C., Zhou, M. & Auerbach, A. Nature 403, 773–776 (2000).
Plested, A. J. R. et al. J. Physiol. (Lond.) 581, 51–73 (2007).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Steinbach, J. Unready for action. Nature 454, 704–705 (2008). https://doi.org/10.1038/454704a
Published:
Issue Date:
DOI: https://doi.org/10.1038/454704a