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Immunology

Sensing the enemy within

Damaged or foreign DNA stimulates immune responses by inducing the production of interferon proteins. New evidence indicates that this response is mediated by a cytosolic DNA sensor known as DAI.

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Figure 1: Recognition of DNA by DAI.

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Chi, H., Flavell, R. Sensing the enemy within. Nature 448, 423–424 (2007). https://doi.org/10.1038/448423a

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