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Genomics

Massively parallel sequencing

A sequencing system has been developed that can read 25 million bases of genetic code — the entire genome of some fungi — within four hours. The technique may provide an alternative approach to DNA sequencing.

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Figure 1: Speeding up sequencing.

References

  1. Venter, J. C. et al. Science 269, 496–512 (1995).

    Article  ADS  Google Scholar 

  2. Venter, J. C. et al. Science 291, 1304–1351 (2001).

    Article  ADS  CAS  Google Scholar 

  3. International Human Genome Mapping Consortium. Nature 409, 860–921 (2001).

  4. Margulies, M. et al. Nature 437, 376–380 (2005).

    Article  ADS  CAS  Google Scholar 

  5. Sanger, F., Nicklen, S. & Coulson, A. R. Proc. Natl Acad. Sci. USA 74, 5463–5467 (1977).

    Article  ADS  CAS  Google Scholar 

  6. Prober, J. M. et al. Science 238, 336–341 (1987).

    Article  ADS  CAS  Google Scholar 

  7. NIH News Release http://www.genome.gov/12513210 (2004).

  8. Nyren, P., Pettersson, B. & Uhlen, M. Anal. Biochem. 208, 171–175 (1993).

    Article  CAS  Google Scholar 

  9. Shendure, J. et al. Science advance online publication doi:10.1126/science.1117389 (2005).

  10. Quake, S. R. et al. Proc. Natl Acad. Sci. USA 100, 3960–3964 (2003).

    Article  ADS  Google Scholar 

Download references

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Rogers, YH., Venter, J. Massively parallel sequencing. Nature 437, 326–327 (2005). https://doi.org/10.1038/437326a

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