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Cytoskeleton

Spindle saga

It's generally been thought that, during cell division, only proteins are necessary to assemble the machine that segregates chromosomes. But a new molecular requirement has been discovered.

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Figure 1: Spindle assembly — proteins and poly(ADP-ribose).

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Karsenti, E. Spindle saga. Nature 432, 563–564 (2004). https://doi.org/10.1038/432563a

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