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Membrane trafficking

Dual-key strategy

Nature volume 429, pages 141–143 (2004)Cite this article

Traffic flow between cellular compartments is controlled by recruitment of cytoplasmic proteins. New work exemplifies a dual-key mechanism, involving membrane lipids and proteins, that coordinates this control.

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Figure 1: Mechanism for the recruitment of the proteins FAPP1 and FAPP2 to the trans-Golgi network (TGN).

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Authors and Affiliations

  1. Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, 06510, Connecticut, USA

    Toshiki Itoh & Pietro De Camilli

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  1. Toshiki Itoh
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  2. Pietro De Camilli
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Itoh, T., De Camilli, P. Dual-key strategy. Nature 429, 141–143 (2004). https://doi.org/10.1038/429141a

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