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Cell biology

Survival in three dimensions

Nature volume 419, pages 790–791 (2002)Cite this article

Whether a cell lives or dies depends on various local cues. New work reveals that those cues include a cell's spatial relationship with its neighbours and polarized interactions with the adjacent extracellular matrix.

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Figure 1: Three-dimensional cell organization and polarity regulate sensitivity to drug-induced apoptosis — a summary of the results of Weaver et al.2.

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Authors and Affiliations

  1. National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Bethesda, 20892-4370, Maryland, USA

    Kenneth M. Yamada & Katherine Clark

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  1. Kenneth M. Yamada
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  2. Katherine Clark
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Correspondence to Kenneth M. Yamada or Katherine Clark.

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Yamada, K., Clark, K. Survival in three dimensions. Nature 419, 790–791 (2002). https://doi.org/10.1038/419790a

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