In situ expression studies show that the selective pathology of Huntington's disease is not explained by a simple pattern of gene expression in the brain.
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References
Strong, T. V. et al. Nature Genet. 5, 259–265 (1993).
Huntington, G. Med. Surg. Reporter 26, 317–321 (1872).
Osler, W. J. Nerv. Ment. Dis. 18, 97–111 (1893).
Vessie, P. R. J. Nerv. Ment. Dis. 76, 553–573 (1932).
Gusella, J. F. et al. Am. J. Hum. Genet. 36, 139 abstr. (1984).
The Huntington's Disease Collaborative Research Group Cell 72, 971–983 (1993).
Brook, J. D. Nature Genet. 3, 279–281 (1993).
Li, S-H. et al. Neuron (in the press).
Little, P. Nature 362, 408–409 (1993).
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Ivinson, A. Huntington's is still holding out. Nature 366, 90 (1993). https://doi.org/10.1038/366090a0
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DOI: https://doi.org/10.1038/366090a0
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