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Apoptosis

Baiting death inhibitors

Enzymes called caspases that start the process of programmed cell death can be dangerous if activated at the wrong time. A feat of self-restraint keeps one such caspase under control.

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Figure 1: The branch of the programmed-cell-death (apoptosis) pathway that includes caspase-9 and its regulators.

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Correspondence to Donald W. Nicholson.

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Nicholson, D. Baiting death inhibitors. Nature 410, 33–34 (2001). https://doi.org/10.1038/35065201

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