Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Brief Communication
  • Published:

Insect metabolism

Preventing cyanide release from leaves

Abstract

Organisms that produce hydrogen cyanide gas to protect themselves against predators can do so by the enzymatic breakdown of a class of compounds known as cyanogens (such as cyanogenic glycosides)1,2. Here we show how a neotropical butterfly, Heliconius sara, can avoid the harmful effects of the cyanogenic leaves of Passiflora auriculata (passion vine), on which its larvae feed exclusively. To our knowledge this is the first example of an insect that is able to metabolize cyanogens and thereby prevent the release of cyanide. The mechanistic details of this pathway might suggest new ways to make cyanogenic crops more useful as a food source.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Structures of sequestered cyanogen from H. sara.

Similar content being viewed by others

References

  1. Spencer, K. C. in Chemical Mediation of Coevolution (ed. Spencer, K. C.) 167–240 (Academic, New York, 1988).

    Book  Google Scholar 

  2. Jones, D. A. Phytochemistry 47 (suppl. 2), 155–162 (1998).

    Article  CAS  Google Scholar 

  3. Gilbert, L. E. Sci. Am. 247, 110–121 (1982).

    Article  Google Scholar 

  4. Jaroszewski, J. W., Andersen, J. V. & Billeskov, I. Tetrahedron 43, 2349–2354 (1987).

    Article  CAS  Google Scholar 

  5. Seigler, D. S. & Brinker, A. M. in Methods in Plant Biochemistry vol. 8 (ed. Waterman, P. G.) 51–131 (Academic, New York, 1993).

    Google Scholar 

  6. Nahrstedt, A. & Davis, R. H. Comp. Biochem. Physiol. 75B, 65–73 (1983).

    CAS  Google Scholar 

  7. Raubenheimer, D. J. Chem. Ecol. 15, 2177–2189 (1989).

    Article  CAS  Google Scholar 

  8. Chamberlain, P. & MacKenzie, R. M. in Cyanide in Biology (eds Vennesland, B., Conn, E. E., Knowles, C. J., Westley, J. & Wissing, F.) 184–196 (Academic, New York, 1981).

    Google Scholar 

  9. Conn, E. E. in Cyanide in Biology (eds Vennesland, B., Conn, E. E., Knowles, C. J., Westley, J. & Wissing, F.) 335–348 (Academic, New York, 1981).

    Google Scholar 

  10. Adsersen, A., Brimer, L., Olsen, C. E. & Jaroszewski, J. W. Phytochemistry 33, 365–367 (1993).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Helene S. Engler.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Engler, H., Spencer, K. & Gilbert, L. Preventing cyanide release from leaves. Nature 406, 144–145 (2000). https://doi.org/10.1038/35018159

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35018159

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing