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  • Brief Communication
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Bioinformatics

Finding genes in Plasmodium falciparum

Abstract

Lawson et al. reply — Pertea et al. report their interpretation of the published Plasmodium falciparum chromosome 3 sequence1using The Institute for Genomic Research's gene-prediction algorithm GlimmerM 2. We believe, however, that their analysis is flawed, and highlights the problem that overreliance on a single algorithm can lead to mistakes in annotation.

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References

  1. Bowman, S. et al. Nature 400, 532–538 (1999).

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  2. Salzberg, S. L. et al. Genomics 59, 24–31 (1999).

    Article  CAS  Google Scholar 

  3. The C. elegans Sequencing Consortium Science 282, 2012–2018 ( 1998).

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Correspondence to Dan Lawson.

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Lawson, D., Bowman, S. & Barrell, B. Finding genes in Plasmodium falciparum . Nature 404, 34–35 (2000). https://doi.org/10.1038/35003646

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