Abstract
Lawson et al. reply — Pertea et al. report their interpretation of the published Plasmodium falciparum chromosome 3 sequence1using The Institute for Genomic Research's gene-prediction algorithm GlimmerM 2. We believe, however, that their analysis is flawed, and highlights the problem that overreliance on a single algorithm can lead to mistakes in annotation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Bowman, S. et al. Nature 400, 532–538 (1999).
Salzberg, S. L. et al. Genomics 59, 24–31 (1999).
The C. elegans Sequencing Consortium Science 282, 2012–2018 ( 1998).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lawson, D., Bowman, S. & Barrell, B. Finding genes in Plasmodium falciparum . Nature 404, 34–35 (2000). https://doi.org/10.1038/35003646
Issue Date:
DOI: https://doi.org/10.1038/35003646
This article is cited by
-
Ab initio gene identification: Prokaryote genome annotation with GeneScan and GLIMMER
Journal of Biosciences (2002)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.